Traditionally used for gastrointestinal symptoms, berberine has emerged as a potent cardiometabolic aid with diverse benefits and mechanisms of action. It has hypoglycemic effects, via both an inhibition of alpha-glucosidase activity and an upregulation of insulin receptors in peripheral tissues, thereby improving insulin sensitivity. Furthermore, it activates Nrf2, a key regulator of cellular antioxidant defense, and attenuates glucose induced neurotoxicity, suggesting a therapeutic potential for diabetic neuropathy.
Unique Features: Hypoglycemic effects via multiple mechanisms, including enhancement of insulin sensitivity.
Favorable effects on blood lipids, including a reduction in triglycerides, and both total and LDL cholesterol.
Activates Nrf-2, a key regulator of antioxidant gene transcription and prevention of glucose-induced neurotoxicity.
Provides 500mg berberine HCL per capsule, the dosing strength used in clinical trials for glucose and lipid control.
Extracted from Berberis vulgaris (European barberry).
Vegetarian capsule.
Supplement Facts:
Serving Size: 1 Capsule.
Amount Per Serving:
Berberine HCL ... 500mg
(from Berberis vulgaris extract) (rhizome).
Suggested Use: Take 1 capsule 2 times daily with meals or as directed by a healthcare professional. Consult a healthcare professional for use beyond 3 months.
This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.